Our custom-made probiotics

Genibio, your partner at every step

Identification of suitable strains

In co-operation with several expert laboratories, Genibio has validated a range of in vitro tests for the evaluation of probiotic potential of lactic acid bacteria and bifidobacteria strains: survival rate in gastroduodenal models, inhibition of the growth of pathogen strains, production of antimicrobial substances, adhesion to the human intestinal mucosa and immunomodulatory properties.

Formulation

We offer original and innovative formulations associating one or more strains and other active components having synergistic effects such as oligosaccharide prebiotics, some trace elements, vitamins and plant extracts. They can also improve the survival rate and growth of probiotic strains during their transit in the human digestive system.

Production

GENIBIO produces bulk mixes of the powder probiotics for the market of food supplements, under various forms ( capsule, sachet, pill). We have developed a complete quality management system, according to ISO 9001, and a food safety system based on a HACCP approach certified ISO 22000, to provide you with safe and compliant products throughout their shelf-life.

Stability

Viability tests are performed throughout the production process to guarantee the presence of viable bacterial population in the finished product in compliance with the recommended daily intake: from some billions to tens of billions of viable microorganisms. Strains are fragile and could easily be damaged during process and storage before use. Thorough ageing studies are carried out systematically in various conditions of temperature and hygrometry. We offer formulations which are stable 2 years at room temperature.

Available strains

Expertise at your service

In order to offer you safe and stable products over time, we have implemented a strict strain evaluation process of available lactic bacteria strains and Bifidobacteria, by using a large panel of tests and controls, from the initial step right through to the finished product.

Taxonomy and food safety

The raw material supplier guarantees the origin, identity, purity and precise taxonomy and genetic stability over time. The selected strains are commonly used in the food industry and are totally safe for human consumption. They are all on the QPS list (Qualified Presumption of Safety, EFSA, 2013).

Example of a gastroduodenal model:

References:

Kuylle S., Sugner M., Le Goff O., Denis S., Blanquet-Diot S., Alric M., Holowacz S., Dubourdeaux M. and Paul F. (2016). Interest of the simplified in vitro gastro-duodeno-ileal model (GDIM) to assess the performance of oral forms of probiotics. J. Int. Soc. Microbiota, vol.3, p.101, DOI: 10.18143/JISM_v3i1.